What is PT-141?
PT-141, also known as Bremelanotide, is a synthetic peptide hormone that was originally developed as a tanning agent before being discovered to have strong aphrodisiac effects. Specifically, PT-141 activates the melanocortin 4 receptor (MC4R) in the brain, triggering pathways linked to sexual arousal and desire.
Some key things to know about PT-141:
- PT-141 is not approved by the FDA but is available from specialized compounding pharmacies as an off-label treatment for low libido and sexual dysfunction. Our partners at Hormone Harmony offer high-quality compounded PT-141 peptides.
- Research shows PT-141 can effectively increase sexual arousal in both men and women by activating central arousal pathways in the hypothalamus.
- When injected under the skin or inhaled nasally, PT-141 has been found to initiate arousal in as little as 20 minutes, with peak effects in 1-2 hours.
- Possible side effects include nausea, flushing, headache, and changes in blood pressure. PT-141 is not recommended for those with heart conditions or on blood pressure medications.
- Typical dosing is 1-2mg injected or inhaled per session. Effects can last 6 hours depending on the individual. For best results, dosing should be optimized under medical supervision.
So in summary, PT-141 Bremelanotide is an exciting peptide hormone therapy that can rekindle sexual desire and performance by directly activating brain arousal centers. As a non-hormonal yet targeted option, PT-141 shows promise for managing common sexual health complaints.
While still considered experimental, early evidence suggests PT-141 could become an important treatment option for both men and women struggling with sexual dysfunction, pending further research on long-term efficacy and safety.